Anti-Proliferation and Anti-Invasion Effects of Diosgenin on Gastric Cancer BGC-823 Cells with HIF-1α shRNAs
Drug resistance is a major factor for the limited efficacy of chemotherapy in gastric cancer treatment. Hypoxia-inducible factor-1α (HIF-1α), a central transcriptional factor in hypoxia, is suggested to participate in the resistance. Here, we identified a hypoxia-mimic (cobalt chloride) sensitive ga...
Main Authors: | Yuan-Neng Chou, Bin Pang, Pin-kang Wei, Ci-An Zhang, Bo Liu, Zhi-Feng Qin, Qian-Jue Tang, Zhu-Jun Mao |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-05-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/13/5/6521 |
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