LIM and SH3 protein 1 regulates cell growth and chemosensitivity of human glioblastoma via the PI3K/AKT pathway

LIM and SH3 protein 1 regulates cell growth and chemosensitivity of human glioblastoma via the PI3K/AKT pathway

Abstract Background LIM and SH3 protein 1 (LASP1) is upregulated in several types of human cancer and implicated in cancer progression. However, the expression and intrinsic function of LASP1 in glioblastoma (GBM) remains unclear. Method Oncomine and The Cancer Genome Atlas (TCGA) database was analy...

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Bibliographic Details
Main Authors: Chuanhong Zhong, Yitian Chen, Bei Tao, Lilei Peng, Tangming Peng, Xiaobo Yang, Xiangguo Xia, Ligang Chen
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
LIM and SH3 protein 1
Glioblastoma
Temozolomide
PI3K/AKT pathway
Online Access:http://link.springer.com/article/10.1186/s12885-018-4649-2

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http://link.springer.com/article/10.1186/s12885-018-4649-2

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