Transcriptional and Ultrastructural Analyses Suggest Novel Insights into Epithelial Barrier Impairment in Celiac Disease

Transcriptional and Ultrastructural Analyses Suggest Novel Insights into Epithelial Barrier Impairment in Celiac Disease

Disruption of epithelial junctional complex (EJC), especially tight junctions (TJ), resulting in increased intestinal permeability, is supposed to activate the enhanced immune response to gluten and to induce the development of celiac disease (CD). This study is aimed to present the role of EJC in C...

Full description

Bibliographic Details
Main Authors: Agnieszka Sowińska, Yasser Morsy, Elżbieta Czarnowska, Beata Oralewska, Ewa Konopka, Marek Woynarowski, Sylwia Szymańska, Maria Ejmont, Michael Scharl, Joanna B. Bierła, Marcin Wawrzyniak, Bożena Cukrowska
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
celiac disease
epithelium
epithelial barrier
tight junctions
adherence junctions
fetal like type enterocytes
Online Access:https://www.mdpi.com/2073-4409/9/2/516

Internet

https://www.mdpi.com/2073-4409/9/2/516

Similar Items