Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls.

Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls.

Sleep disturbance is associated with the development of obesity, diabetes and hepatic steatosis in murine models. Hepatic triglyceride accumulation oscillates in a circadian rhythm regulated by clock genes, light-dark cycle and feeding time in mice. The role of the sleep-wake cycle in the pathogenes...

Full description

Bibliographic Details
Main Authors: Christine Bernsmeier, Diego M Weisskopf, Marlon O Pflueger, Jan Mosimann, Benedetta Campana, Luigi Terracciano, Christoph Beglinger, Markus H Heim, Christian Cajochen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4648512?pdf=render

Internet

http://europepmc.org/articles/PMC4648512?pdf=render

Similar Items