Minimizing the number of optimizations for efficient community dynamic flux balance analysis.

Dynamic flux balance analysis uses a quasi-steady state assumption to calculate an organism's metabolic activity at each time-step of a dynamic simulation, using the well-known technique of flux balance analysis. For microbial communities, this calculation is especially costly and involves solv...

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Bibliographic Details
Main Authors: James D Brunner, Nicholas Chia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007786