Quantifying the Metabolic Signature of Multiple Sclerosis by in vivo Proton Magnetic Resonance Spectroscopy: Current Challenges and Future Outlook in the Translation From Proton Signal to Diagnostic Biomarker

Quantifying the Metabolic Signature of Multiple Sclerosis by in vivo Proton Magnetic Resonance Spectroscopy: Current Challenges and Future Outlook in the Translation From Proton Signal to Diagnostic Biomarker

Proton magnetic resonance spectroscopy (1H-MRS) offers a growing variety of methods for querying potential diagnostic biomarkers of multiple sclerosis in living central nervous system tissue. For the past three decades, 1H-MRS has enabled the acquisition of a rich dataset suggestive of numerous meta...

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Bibliographic Details
Main Authors: Kelley M. Swanberg, Karl Landheer, David Pitt, Christoph Juchem
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
multiple sclerosis
in vivo proton magnetic resonance spectroscopy 1H-MRS
biomarker
longitudinal relaxation T1
transverse relaxation T2
spectroscopic baseline
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01173/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.01173/full

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