Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes

Introduction Renal tubular injury contributes to the decline in kidney function in patients with diabetes. Cell type-specific DNA methylation patterns have been used to calculate proportions of particular cell types. In this study, we developed a method to detect renal tubular injury in patients wit...

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Bibliographic Details
Main Authors: Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Daigoro Hirohama, Toshikazu Okaneya, Kazunari Yuki, Yoshihito Atsumi, Atsuhisa Sato, Eri Arai, Yae Kanai, Tatsuo Shimosawa, Toshiro Fujita
Format: Article
Language:English
Published: BMJ Publishing Group 2020-04-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/8/1/e001501.full