Molecular Docking and Molecular Dynamics Simulation studies of DHFR inhibitors in Plasmodium falciparum

Malaria, caused by Plasmodium falciparum is a very common disease that causes 2.5 million deaths worldwide. This makes designing of lead molecules for malaria very exigent. DHFR has been known to be one of the major targets of antimalarial drug therapy which functions as a fundamental cofactor in th...

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Bibliographic Details
Main Authors: Prachi Bhole, Kiran Bharat Lokhande, Shuchi Nagar, K. Venkateswara Swamy
Format: Article
Language:English
Published: Science Planet Inc. 2017-10-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a11.pdf