Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis

Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis

Psychosis is accompanied by severe attentional deficits, and impairments in associational-memory processing and sensory information processing that are ascribed to dysfunctions in prefrontal and hippocampal function. Disruptions of glutamatergic signalling may underlie these alterations: Antagonism...

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Bibliographic Details
Main Authors: Thomas eGrüter, Valentina eWiescholleck, Valentyna eDubovik, Verena eAliane, Denise eManahan-Vaughan
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Hippocampus
Schizophrenia
GABA
in vivo
MK801
NMDA receptor hypofunction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00117/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00117/full

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