Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats

Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats

Astragaloside II (AS II), a novel saponin purified from Astragalus membranes, has been reported to modulate the immune response, repair tissue injury, and prevent inflammatory response. However, the protective effects of AS II on podocyte injury in diabetic nephropathy (DN) have not been investigate...

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Bibliographic Details
Main Authors: Jun Su, Chongting Gao, Ling Xie, Ying Fan, Yilan Shen, Qunwei Huang, Niansong Wang, Youhua Xu, Nizhi Yang, Dingkun Gui
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
diabetic nephrology
astragaloside II
podocyte injury
mitochondrial dynamics
mitophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.638422/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.638422/full

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