Role of Epigenetic Histone Modifications in Diabetic Kidney Disease Involving Renal Fibrosis

One of the commonest causes of end-stage renal disease is diabetic kidney disease (DKD). Renal fibrosis, characterized by the accumulation of extracellular matrix (ECM) proteins in glomerular basement membranes and the tubulointerstitium, is the final manifestation of DKD. The TGF-β pathway triggers...

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Bibliographic Details
Main Authors: Jing Sun, Yangwei Wang, Wenpeng Cui, Yan Lou, Guangdong Sun, Dongmei Zhang, Lining Miao
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2017/7242384