Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis

Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis

Cells have multiple means to induce apoptosis in response to viral infection. Poxviruses must prevent activation of cellular apoptosis to ensure successful replication. These viruses devote a substantial portion of their genome to immune evasion. Many of these immune evasion products expressed durin...

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Bibliographic Details
Main Authors: Daniel Brian Nichols, William De Martini, Jessica Cottrell
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Viruses
Subjects:
poxvirus
Vaccinia Virus
Molluscum Contagiosum Virus
Myxoma Virus
apoptosis
immune evasion
mitochondrial membrane permeabilization
protein kinase R
caspase
host defense
Online Access:https://www.mdpi.com/1999-4915/9/8/215

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https://www.mdpi.com/1999-4915/9/8/215

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