Identification of anti‐Parkinson's Disease Lead Compounds from Aspergillus ochraceus Targeting Adenosin Receptors A2A

Identification of anti‐Parkinson's Disease Lead Compounds from Aspergillus ochraceus Targeting Adenosin Receptors A2A

Abstract Two novel alkaloids compounds together with fifteen know metabolites were identified from Aspergillus ochraceus. The stereochemistry features of the new molecules were determined via HRESIMS, NMR, ECD, and XRD analyses. Amongst these, compounds two compounds exhibited potential efficacy as...

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Bibliographic Details
Main Authors: Prof. Linzhen Hu, Shuying Tian, Rongrong Wu, Zhou Tong, Wen Jiang, Ping Hu, Xueyang Xiao, Xueke Zhang, Hui Zhou, Prof. Qingyi Tong, Dr. Yuanyuan Lu, Prof. Zhiyong Huang, Prof. Yong Chen, Prof. Yonghui Zhang
Format: Article
Language:English
Published: Wiley-VCH 2021-06-01
Series:ChemistryOpen
Subjects:
adenosine receptors
Aspergillus ochraceus
alkaloids
drug discovery
Parkinson's disease
virtual screening
Online Access:https://doi.org/10.1002/open.202100022

Internet

https://doi.org/10.1002/open.202100022

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