Determining physical constraints in transcriptional initiation complexes using DNA sequence analysis.

Eukaryotic gene expression is often under the control of cooperatively acting transcription factors whose binding is limited by structural constraints. By determining these structural constraints, we can understand the "rules" that define functional cooperativity. Conversely, by understand...

Full description

Bibliographic Details
Main Authors: Ryan K Shultzaberger, Derek Y Chiang, Alan M Moses, Michael B Eisen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2077805?pdf=render