Is the Cell Nucleus a Necessary Component in Precise Temporal Patterning?

One of the functions of the cell nucleus is to help regulate gene expression by controlling molecular traffic across the nuclear envelope. Here we investigate, via stochastic simulation, what effects, if any, does segregation of a system into the nuclear and cytoplasmic compartments have on the stoc...

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Bibliographic Details
Main Authors: Jaroslav Albert, Marianne Rooman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4520485?pdf=render