AP-2α Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes

AP-2α and c-MYC are important transcription factors involved in multiple cellular processes. They each display the paradoxical capacities to stimulate both cell proliferation and apoptosis under different conditions. In the present study we found that over expression of c-MYC was associated with acc...

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Bibliographic Details
Main Authors: Lei Yu, Michael J. Hitchler, Wenqing Sun, Ehab H. Sarsour, Prabhat C. Goswami, Aloysius J. Klingelhutz, Frederick E. Domann
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2009/780874