Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation

Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation

Abstract Background Ketogenic diets (KDs) or short-term fasting are popular trends amongst supportive approaches for cancer patients. Beta-hydroxybutyrate (3-OHB) is the main physiological ketone body, whose concentration can reach plasma levels of 2–6 mM during KDs or fasting. The impact of 3-OHB o...

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Bibliographic Details
Main Authors: Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto, Ulrike Kämmerer
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Cancer & Metabolism
Subjects:
Ketogenic diet
β-Hydroxybutyrate
Ketone bodies
Breast cancer
Seahorse
Metabolic profile
Online Access:http://link.springer.com/article/10.1186/s40170-018-0180-9

Internet

http://link.springer.com/article/10.1186/s40170-018-0180-9

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