Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V.

Measles virus (MeV) is dual-tropic: it replicates first in lymphatic tissues and then in epithelial cells. This switch in tropism raises the question of whether, and how, intra-host evolution occurs. Towards addressing this question, we adapted MeV either to lymphocytic (Granta-519) or epithelial (H...

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Bibliographic Details
Main Authors: Ryan C Donohue, Christian K Pfaller, Roberto Cattaneo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007605