Dual function of novel pollen coat (surface) proteins: IgE-binding capacity and proteolytic activity disrupting the airway epithelial barrier.

BACKGROUND: The pollen coat is the first structure of the pollen to encounter the mucosal immune system upon inhalation. Prior characterizations of pollen allergens have focused on water-soluble, cytoplasmic proteins, but have overlooked much of the extracellular pollen coat. Due to washing with org...

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Bibliographic Details
Main Authors: Mohamed Elfatih H Bashir, Jason M Ward, Matthew Cummings, Eltayeb E Karrar, Michael Root, Abu Bekr A Mohamed, Robert M Naclerio, Daphne Preuss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3538775?pdf=render