Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues.

NAD plays essential redox and non-redox roles in cell biology. In mammals, its de novo and recycling biosynthetic pathways encompass two independent branches, the "amidated" and "deamidated" routes. Here we focused on the indispensable enzymes gating these two routes, i.e. nicoti...

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Bibliographic Details
Main Authors: Valerio Mori, Adolfo Amici, Francesca Mazzola, Michele Di Stefano, Laura Conforti, Giulio Magni, Silverio Ruggieri, Nadia Raffaelli, Giuseppe Orsomando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4244216?pdf=render