Functional characteristics of Th1, Th17, and ex-Th17 cells in EAE revealed by intravital two-photon microscopy
Abstract Background T helper (Th) 17 cells are a highly plastic subset of T cells, which in the context of neuroinflammation, are able to acquire pathogenic features originally attributed to Th1 cells (resulting in so called ex-Th17 cells). Thus, a strict separation between the two T cell subsets in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-020-02021-x |