Disintegrins: integrin selective ligands which activate integrin-coupled signaling and modulate leukocyte functions

Disintegrins: integrin selective ligands which activate integrin-coupled signaling and modulate leukocyte functions

Extracellular matrix proteins and cell adhesion receptors (integrins) play essential roles in the regulation of cell adhesion and migration. Interactions of integrins with the extracellular matrix proteins lead to phosphorylation of several intracellular proteins such as focal adhesion kinase, activ...

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Bibliographic Details
Main Authors: Barja-Fidalgo C., Coelho A.L.J., Saldanha-Gama R., Helal-Neto E., Mariano-Oliveira A., Freitas M.S. de
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Integrin
Disintegrin
Leukocytes
Activation
Proliferation
Signal transduction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001000008

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