Does applicability domain exist in microarray-based genomic research?

Constructing an accurate predictive model for clinical decision-making on the basis of a relatively small number of tumor samples with high-dimensional microarray data remains a very challenging problem. The validity of such models has been seriously questioned due to their failure in clinical valid...

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Bibliographic Details
Main Authors: Li Shao, Leihong Wu, Hong Fang, Weida Tong, Xiaohui Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2883551?pdf=render