The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological features including β-amyloid (Aβ) peptide accumulation, oxidative damage, and cell death. The causes of AD and AMD are not known but...

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Bibliographic Details
Main Authors: Dasari Bhanu, Prasanthi Jaya RP, Marwarha Gurdeep, Singh Brij B, Ghribi Othman
Format: Article
Language:English
Published: BMC 2010-09-01
Series:BMC Ophthalmology
Online Access:http://www.biomedcentral.com/1471-2415/10/22