Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine

Self-reinoculation with fecal flora changes microbiota density and composition leading to an altered bile-acid profile in the mouse small intestine

Abstract Background The upper gastrointestinal tract plays a prominent role in human physiology as the primary site for enzymatic digestion and nutrient absorption, immune sampling, and drug uptake. Alterations to the small intestine microbiome have been implicated in various human diseases, such as...

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Bibliographic Details
Main Authors: Said R. Bogatyrev, Justin C. Rolando, Rustem F. Ismagilov
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Microbiome
Subjects:
Microbial quantification
Metabolomics analyses
Mouse models
Small intestine microbiota
Bile acids
Deconjugation
Online Access:https://doi.org/10.1186/s40168-020-0785-4

Internet

https://doi.org/10.1186/s40168-020-0785-4

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