Engineering a Fibrocartilage Spectrum through Modulation of Aggregate Redifferentiation
Expanded costochondral cells provide a clinically relevant cell source for engineering both fibrous and hyaline articular cartilage. Expanding chondrocytes in a monolayer results in a shift toward a proliferative, fibroblastic phenotype. Three-dimensional aggregate culture may, however, be used to r...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2015-02-01
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| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368913X676204 |