Subcutaneous transplantation of engineered islet/adipose-derived mesenchymal stem cell sheets in diabetic pigs with total pancreatectomy

Introduction: Intraportal islet transplantation is a promising therapeutic approach for patients with type 1 diabetes mellitus (T1DM). However, despite being minimally invasive, the method has some limitations, such as short-term graft loss, portal venous thrombosis, and difficulty in collecting ade...

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Bibliographic Details
Main Authors: Mampei Yamashita, Toshiyuki Adachi, Tomohiko Adachi, Shinichiro Ono, Naomi Matsumura, Kyoichiro Maekawa, Yusuke Sakai, Masaaki Hidaka, Kengo Kanetaka, Tamotsu Kuroki, Susumu Eguchi
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Regenerative Therapy
Subjects:
Pig
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420301012