Predictive significance of kidney myeloid-related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases.

BACKGROUND AND OBJECTIVE: We have reported that toll-like receptor 4 (TLR4) and one of its endogenous ligands, myeloid-related protein 8 (MRP8 or S100A8), play an important role in the progression of diabetic nephropathy in mice. The aim of this study was to evaluate significance of kidney MRP8 expr...

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Main Authors: Takashige Kuwabara, Kiyoshi Mori, Masato Kasahara, Hideki Yokoi, Hirotaka Imamaki, Akira Ishii, Kenichi Koga, Akira Sugawara, Shinji Yasuno, Kenji Ueshima, Takashi Morikawa, Yoshio Konishi, Masahito Imanishi, Akira Nishiyama, Kazuwa Nakao, Masashi Mukoyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3928329?pdf=render