Targeted Polymeric Nanoparticles for Brain Delivery of High Molecular Weight Molecules in Lysosomal Storage Disorders.

Targeted Polymeric Nanoparticles for Brain Delivery of High Molecular Weight Molecules in Lysosomal Storage Disorders.

Lysosomal Storage Disorders (LSDs) are a group of metabolic syndromes, each one due to the deficit of one lysosomal enzyme. Many LSDs affect most of the organ systems and overall about 75% of the patients present neurological impairment. Enzyme Replacement Therapy, although determining some systemic...

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Bibliographic Details
Main Authors: Marika Salvalaio, Laura Rigon, Daniela Belletti, Francesca D'Avanzo, Francesca Pederzoli, Barbara Ruozi, Oriano Marin, Maria Angela Vandelli, Flavio Forni, Maurizio Scarpa, Rosella Tomanin, Giovanni Tosi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4881964?pdf=render

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http://europepmc.org/articles/PMC4881964?pdf=render

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