lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice

lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice

Long non-coding RNA (lncRNA) X-inactive specific transcript (Xist) is involved in apoptosis and inflammatory injury. This study aimed to assess the role of lncRNA Xist in sevoflurane-induced social and emotional impairment and neuronal apoptosis in neonatal mice and hippocampal neuronal cells. The p...

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Bibliographic Details
Main Authors: Lili Xu, Qi Xu, Shaobing Dai, Cuicui Jiao, Yingying Tang, Jiaqian Xie, Hui Wu, Xinzhong Chen
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
sevoflurane
neurotoxicity
apoptosis
lncRNA Xist
miR-98-5p
EDEM1
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001049

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http://www.sciencedirect.com/science/article/pii/S2162253121001049

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