Measuring heterogeneity in normative models as the effective number of deviation patterns.

Normative modeling is an increasingly popular method for characterizing the ways in which clinical cohorts deviate from a reference population, with respect to one or more biological features. In this paper, we extend the normative modeling framework with an approach for measuring the amount of hete...

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Bibliographic Details
Main Authors: Abraham Nunes, Thomas Trappenberg, Martin Alda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242320