HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV

<p>Abstract</p> <p>It is well established that HIV-1 infection typically involves an interaction between the viral envelope protein gp120/41 and the CD4 molecule followed by a second interaction with a chemokine receptor, usually CCR5 or CXCR4. In the early stages of an HIV-1 infec...

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Bibliographic Details
Main Authors: Cicala Claudia, Arthos James, Fauci Anthony
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/S1/S2