Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids

Prostate cancer (PCa) is the second leading cause of cancer-related mortality and morbidity among males worldwide. Deciphering the biological mechanisms and molecular pathways involved in PCa pathogenesis and progression has been hindered by numerous technical limitations mainly attributed to the li...

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Bibliographic Details
Main Authors: Katia Cheaito, Hisham F. Bahmad, Hiba Jalloul, Ola Hadadeh, Hiba Msheik, Albert El-Hajj, Deborah Mukherji, Mohamed Al-Sayegh, Wassim Abou-Kheir
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
prostate epithelial cells
prostate cancer
organoids
lineage markers
RNA-seq
EGF
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.571677/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.571677/full

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