FGF23, a novel muscle biomarker detected in the early stages of ALS

Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive muscle weakness. Skeletal muscle is a prime source for biomarker discovery since it is one of the earliest sites to manifest disease pathology. From a prior RNA sequencing project, we ident...

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Bibliographic Details
Main Authors: Ying Si, Mohamed Kazamel, Michael Benatar, Joanne Wuu, Yuri Kwon, Thaddaeus Kwan, Nan Jiang, Dominik Kentrup, Christian Faul, Lyndsy Alesce, Peter H. King
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91496-6