A Combined Experimental and Computational Study of Vam3, a Derivative of Resveratrol, and Syk Interaction

Spleen tyrosine kinase (Syk) plays an indispensable role through preliminary extracellular antigen-induced crosslinking of Fc receptor (FcR) in the pathogenesis of autoimmune disorders, such as rheumatoid arthritis. In this study, we identify Vam3, a dimeric derivative of resveratrol isolated from...

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Bibliographic Details
Main Authors: Ming Jiang, Renping Liu, Ying Chen, Qisheng Zheng, Saijun Fan, Peixun Liu
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
Syk
Online Access:http://www.mdpi.com/1422-0067/15/9/17188