Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression.

In the zebrafish, Fgf and Hh signalling assign anterior and posterior identity, respectively, to the poles of the developing ear. Mis-expression of fgf3 or inhibition of Hh signalling results in double-anterior ears, including ectopic expression of hmx3a. To understand how this double-anterior patte...

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Bibliographic Details
Main Authors: Ryan D Hartwell, Samantha J England, Nicholas A M Monk, Nicholas J van Hateren, Sarah Baxendale, Mar Marzo, Katharine E Lewis, Tanya T Whitfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008051