Reactions of 3-(p-substituted-phenyl)-5-chloromethyl-1,2,4-oxadiazoles with KCN leading to acetonitriles and alkanes via a non-reductive decyanation pathway

The present work describes an unfamiliar reaction of 5-(chloromethyl)-3-substituted-phenyl-1,2,4-oxadiazoles with KCN affording trisubstituted 1,2,4-oxadiazol-5-ylacetonitriles and their parent alkanes, namely, 1,2,3-trisubstituted-1,2,4-oxadiazol-5-ylpropanes. To the best of our knowledge, the curr...

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Bibliographic Details
Main Authors: Akın Sağırlı, Yaşar Dürüst
Format: Article
Language:English
Published: Beilstein-Institut 2018-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
KCN
Online Access:https://doi.org/10.3762/bjoc.14.280