COX-2 gene expression in colon cancer tissue related to regulating factors and promoter methylation status

<p>Abstract</p> <p>Background</p> <p>Increased cyclooxygenase activity promotes progression of colorectal cancer, but the mechanisms behind COX-2 induction remain elusive. This study was therefore aimed to define external cell signaling and transcription factors relatin...

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Bibliographic Details
Main Authors: Lagerstedt Kristina, Lönnroth Christina, Andersson Marianne, Carén Helena, Asting Annika, Lundholm Kent
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/238