E-Cadherin Protects Primary Hepatocyte Spheroids from Cell Death by a Caspase-Independent Mechanism

Cultivation of primary hepatocytes as spheroids creates an efficient three-dimensional model system for hepatic studies in vitro and as a cell source for a spheroid reservoir bioartificial liver. The mechanism of spheroid formation is poorly understood, as is an explanation for why normal, anchorage...

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Bibliographic Details
Main Authors: Jennifer L. Luebke-Wheeler, Geir Nedredal, Le Yee, Bruce P. Amiot, Scott L. Nyberg
Format: Article
Language:English
Published: SAGE Publishing 2009-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368909X474258