125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts

Abstract Background Lung cancer is a fatal disease and a serious health problem worldwide. Patients are usually diagnosed at an advanced stage, and the effectiveness of chemotherapy for such patients is very limited. Iodine 125 seed (125I) irradiation can be used as an important adjuvant treatment f...

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Bibliographic Details
Main Authors: Qing Jin, Cunzhi Lin, Xinhong Zhu, Yiwei Cao, Caihong Guo, Lijun Wang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Radiation Oncology
Subjects:
P21
Online Access:http://link.springer.com/article/10.1186/s13014-020-01682-5