Effect of sodium bicarbonate administration on mortality in patients with lactic acidosis: a retrospective analysis.

BACKGROUND: Lactic acidosis is a common cause of high anion gap metabolic acidosis. Sodium bicarbonate may be considered for an arterial pH <7.15 but paradoxically depresses cardiac performance and exacerbates acidosis by enhancing lactate production. This study aimed to evaluate the cause and mo...

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Bibliographic Details
Main Authors: Hyun Jeong Kim, Young Ki Son, Won Suk An
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3673920?pdf=render