Comparison between the Effect of Cow Ghee and Butter on Memory and Lipid Profile of Wistar Rats
Introduction: The traditional texts designate Cow Ghee as Medhya Rasayana, beneficial for mental alertness and memory. There has been concern about increased risk of cardiovascular disease due to its high percentage of saturated fatty acids in ghee. Amongst all edible fats, nutrition composition...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-09-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/8512/19457_CE[Ra]_F(P)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Introduction: The traditional texts designate Cow Ghee as
Medhya Rasayana, beneficial for mental alertness and memory.
There has been concern about increased risk of cardiovascular
disease due to its high percentage of saturated fatty acids in
ghee. Amongst all edible fats, nutrition composition of cow
ghee and butter is comparatively similar. Hence we had planned
a study to assess effect of cow ghee on memory and lipid
profile.
Aim: So the aim of this study is to assess the effect of cow ghee
on memory and lipid profile
Materials and Methods: Nootropic activity of test drugs was
assessed by Elevated Plus Maze (EPM) and Morris Water Maze
(MWM) model. Rats were divided into four groups namely
control, Piracetam, cow ghee and butter. All drugs were given
orally for 21 days. Transfer latency was measured in EPM model
and probe test was done in MWM model.
Results: Cow ghee and butter group showed no significant
effect on memory in EPM and MWM model. There was reduction
in weight of animals in Cow Ghee group and increase in weight
with Butter. In both the models there was a significant increase
in Triglyceride (TG) and Very Low Density Lipoproteins (VLDL)
levels of rats in butter groups and increase in TG and VLDL of
rats with cow ghee in EPM model.
Conclusion: The result of experiment suggests that no beneficial
effect cow ghee and butter on cognition was seen. However,
ghee is relatively safer when compared to Butter in considering
lipid profile. |
|---|---|
| ISSN: | 2249-782X 0973-709X |