A Novel Role for Polycystin-2 (Pkd2) in <i>P. tetraurelia</i> as a Probable Mg<sup>2+</sup> Channel Necessary for Mg<sup>2+</sup>-Induced Behavior

A Novel Role for Polycystin-2 (Pkd2) in <i>P. tetraurelia</i> as a Probable Mg<sup>2+</sup> Channel Necessary for Mg<sup>2+</sup>-Induced Behavior

A human ciliopathy gene codes for Polycystin-2 (Pkd2), a non-selective cation channel. Here, the Pkd2 channel was explored in the ciliate <i>Paramecium tetraurelia</i> using combinations of RNA interference, over-expression, and epitope-tagging, in a search for function and novel interac...

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Bibliographic Details
Main Authors: Megan S. Valentine, Junji Yano, Judith Van Houten
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Genes
Subjects:
Polycystin-2
channelopathy
cilia
cell body membrane
magnesium channel
electrophysiology
behavior
over-expression
trafficking
Online Access:https://www.mdpi.com/2073-4425/10/6/455

Internet

https://www.mdpi.com/2073-4425/10/6/455

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