Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells

<p>Abstract</p> <p>In the present study, we explore the role of apoptosis signal-regulating kinase 1 (ASK1) in denbinobin-induced apoptosis in human lung adenocarcinoma (A549) cells. Denbinobin-induced cell apoptosis was attenuated by an ASK1 dominant-negative mutant (ASK1DN), two...

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Main Authors: Pan Shiow-Lin, Teng Che-Ming, Chen Mei-Chieh, Chen Chien-Chih, Hsu Ming-Jen, Weng Chih-Ming, Yu Chung-Chi, Chen Bing-Chang, Kuo Chen-Tzu, Bien Mauo-Ying, Shih Chung-Hung, Lin Chien-Huang
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/43