Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer

Novel Docosahexaenoic Acid Ester of Phloridzin Inhibits Proliferation and Triggers Apoptosis in an In Vitro Model of Skin Cancer

Skin cancer is among the most common cancer types accompanied by rapidly increasing incidence rates, thus making the development of more efficient therapeutic approaches a necessity. Recent studies have revealed the potential role of decosahexaenoic acid ester of phloridzin (PZDHA) in suppressing pr...

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Bibliographic Details
Main Authors: Theodora Mantso, Dimitrios T. Trafalis, Sotiris Botaitis, Rodrigo Franco, Aglaia Pappa, H. P. Vasantha Rupasinghe, Mihalis I. Panayiotidis
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Antioxidants
Subjects:
phloridzin
docosahexaenoic acid
flavonoids
skin cancer
melanoma
epidermoid carcinoma
apoptosis
necrosis
cell cycle
oxidative stress
reactive oxygen species
Online Access:https://www.mdpi.com/2076-3921/7/12/188

Internet

https://www.mdpi.com/2076-3921/7/12/188

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