Modulation of Alloimmune Responses by Interleukin-10 Prevents Rejection of Implanted Allogeneic Smooth Muscle Cells and Restores Postinfarction Ventricular Function

Modulation of Alloimmune Responses by Interleukin-10 Prevents Rejection of Implanted Allogeneic Smooth Muscle Cells and Restores Postinfarction Ventricular Function

Interleukin-10 (IL-10) gene transduction into allogeneic smooth muscle cells (SMCs) was evaluated to improve the long-term benefits of allogeneic cell transplantation into infarcted myocardium. Allogeneic cells, including SMCs, have been demonstrated to restore cardiac function and repair the infarc...

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Bibliographic Details
Main Authors: Sanjiv Dhingra, Jun Wu, Shu-Hong Li, Jian Guo, Xi-Ping Huang, Anton Mihic, Jim Hu, Richard D. Weisel, Ren-Ke Li M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2015-06-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X681036

Internet

https://doi.org/10.3727/096368914X681036

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