Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway

Chidamide Inhibits Acute Myeloid Leukemia Cell Proliferation by lncRNA VPS9D1-AS1 Downregulation via MEK/ERK Signaling Pathway

Irregular histone modification and aberrant lncRNAs expression are closely related to the occurrence of tumors including acute myeloid leukemia (AML). However, the effects and specific underlying molecular mechanism of histone deacetylase inhibitors on lncRNA expression in AML cells are unclear. Her...

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Bibliographic Details
Main Authors: Liman Lin, Yimei Que, Pingfan Lu, Huimin Li, Min Xiao, Xiaojian Zhu, Dengju Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
chidamide
VPS9D1-AS1
MEK/ERK signaling pathway
proliferation
long non-coding RNA
acute myeloid leukemia
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.569651/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.569651/full

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