Role of Orexin in the Tolerance and Physical Dependence to Morphine

BACKGROUND AND OBJECTIVE: Although opioid drugs cause analgesia and more effective in treatment of pain but, its utility is hindered by the development of tolerance to its analgesic effects. Orexin A and B (hypocretin 1 and 2) discovered in 1998 and projected to large areas of the brain regions invo...

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Bibliographic Details
Main Authors: Samad Nazemi, Hassan Azhdari zarmrhri, Hashem Haghdoost-Yazdi
Format: Article
Language:English
Published: Babol University of Medical Sciences 2014-12-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Subjects:
Online Access:http://jbums.org/browse.php?a_code=A-10-1453-3&slc_lang=en&sid=1