Ionizing Radiation-Induced Extracellular Vesicle Release Promotes AKT-Associated Survival Response in SH-SY5Y Neuroblastoma Cells

Ionizing Radiation-Induced Extracellular Vesicle Release Promotes AKT-Associated Survival Response in SH-SY5Y Neuroblastoma Cells

Radiation therapy is one of the most effective methods of tumor eradication; however, in some forms of neuroblastoma, radiation can increase the risk of secondary neoplasms, due to the ability of irradiated cells to transmit pro-survival signals to non-irradiated cells through vesicle secretion. The...

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Bibliographic Details
Main Authors: Flavia Tortolici, Simone Vumbaca, Bernadette Incocciati, Renu Dayal, Katia Aquilano, Anna Giovanetti, Stefano Rufini
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
X-rays
exosomes
EVs
radiotherapy
radio-resistance
EMT
Online Access:https://www.mdpi.com/2073-4409/10/1/107

Internet

https://www.mdpi.com/2073-4409/10/1/107

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