DNA variants affecting the expression of numerous genes in trans have diverse mechanisms of action and evolutionary histories.

DNA variants that alter gene expression contribute to variation in many phenotypic traits. In particular, trans-acting variants, which are often located on different chromosomes from the genes they affect, are an important source of heritable gene expression variation. However, our knowledge about t...

Full description

Bibliographic Details
Main Authors: Sheila Lutz, Christian Brion, Margaret Kliebhan, Frank W Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008375